Leveraging genetically simple traits to identify small-effect variants for complex phenotypes

BMC Genomics

Table 1 Genomic regions with overlapping QTL between milk production and composition traits

BTAU6	Region (Mb)	Milk production traits	Milk composition traits
1	144.2–144.65	MY, F%, P%	phosphorus
3	7.7–8.15	P%	IgG
6	37.4–37.95	F%, P%	lactose%
6	87.15–87.65	MY, PY, P%	κ-casein
11	103.1–103.55	FY, MY, PY, F%	β-lactoglobulin
14	1.60–2.25	FY, MY, PY, F%, P%	Ca, S, P, κCN
17	56.35–56.6	FY, PY	calcium
20	33.35–33.75	P%	lacto-peroxidase

Milk production traits are FY = fat yield (kg/lactation), MY = milk yield (L/lactation), PY = protein yield (kg/lactation), F% = fat percentage in milk, P% = protein percentage in milk. Milk composition traits include phosphorus (P, mg/kg), IgG (mg/g), κ-casein (κCN, mg/g), β-lactoglobulin (mg/g), calcium (Ca, mg/kg), sulphur (S, mg/kg) and lacto-peroxidase (mg/g) concentration in milk

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