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Table 3 Top 10 GO Term and Broad MSigDB Canonical Pathway enrichments for 2 most correlated modules in PPvNN

From: Network analysis of psoriasis reveals biological pathways and roles for coding and long non-coding RNAs

Module

GO Term

pGO

Broad MSigDB Canonical Pathway

pBroad

Blue

lipid biosynthetic process

2.50E-61

Genes involved in Metabolism of lipids and lipoproteins

6.10E-71

fatty acid metabolic process

4.10E-57

Peroxisome

5.30E-39

mitochondrial matrix

3.90E-53

Valine, leucine and isoleucine degradation

5.60E-35

mitochondrial membrane

3.00E-52

Genes involved in Generic Transcription Pathway

6.90E-34

mitochondrial inner membrane

2.20E-51

Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism

5.90E-32

organic acid catabolic process

1.70E-48

Genes involved in Cholesterol biosynthesis

2.90E-26

peroxisome

5.30E-42

Genes involved in The citric acid (TCA) cycle and respiratory electron transport

6.40E-23

microbody

5.30E-42

Fatty acid metabolism

1.20E-20

cofactor binding

5.40E-40

Propanoate metabolism

2.40E-20

steroid metabolic process

3.00E-36

Genes involved in Phospholipid metabolism

2.60E-18

Salmon

immune effector process

0.0001

Olfactory transduction

3.20E-16

innate immune response

0.0002

Genes involved in Olfactory Signaling Pathway

2.70E-12

cell surface

0.0002

Genes involved in Hyaluronan uptake and degradation

5.90E-05

lymphocyte mediated immunity

0.0002

Genes involved in Hyaluronan metabolism

0.0001

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

0.0003

Genes involved in Glycosaminoglycan metabolism

0.0003

adaptive immune response

0.0004

Sulfur metabolism

0.0006

leukocyte mediated immunity

0.0004

Genes involved in Chondroitin sulfate biosynthesis

0.0009

ion channel activity

0.0005

Glycosaminoglycan biosynthesis - chondroitin sulfate

0.001

positive regulation of immune response

0.0005

PAR1-mediated thrombin signaling events

0.001

response to bacterium

0.0006

Genes involved in Developmental Biology

0.0013