Fig. 3
From: Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq
The Venn Diagram shows RNA-seq data for all RNA biotypes (protein-coding and non-coding) that were regulated by diabetes compared to control (DvC) and by P78 treated compared to non-treated diabetic controls (TvD). FC: fold changes. Blue: DvC - positive FC (FC > 0). Green: DvC - negative FC (FC < 0). Pink: TvD - positive FC (FC > 0). Yellow: TvD - negative FC (FC < 0). Changes in expression levels were seen in 1237 transcripts of which 208 were regulated by both diabetes and treatment. 1129 transcripts were regulated in DN, 316 by treatment (early and late), and 138 whose expression levels were altered in DN were reversed by treatment towards control levels (q < 0.05)