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Table 1 Number of all transcripts (coding and non-coding) that were significantly regulated in the kidney by diabetes (D), P78 treatment (T, early and late treatment), and those with expression changes in D that were reversed by T in the Ins2 Akita mouse model of diabetic nephropathy (DN) (q < 0.05)

From: Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq

Group

# of Genes

Upregulated in D

164

Downregulated in D

965

Upregulated with T

183

Downregulated with T

133

Upregulated in D, reversed by T

51

Downregulated in D, reversed by T

87