Table 2 Number of protein-coding (mRNA) genes that were significantly regulated in the kidney by diabetes and by P78 treatment compared to non-diabetic controls, and those with expression changes in diabetes that were reversed towards normal levels by P78 treatment in the Ins2 Akita mice with FC > (+/-)1 (q < 0.05)
From: Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq
Group | # of Genes |
|---|---|
Upregulated in D | 71 |
Downregulated in D | 830 |
Upregulated with T | 65 |
Downregulated with T | 56 |
Upregulated in D, reversed by T | 15 |
Downregulated in D, reversed by T | 34 |