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Table 2 Identification of potential RDs for lineage classification in Mtb lineages with existing RD markers

From: In silico region of difference (RD) analysis of Mycobacterium tuberculosis complex from sequence reads using RD-Analyzer

Lineage Sample size Existing RD markers RD detected
Name Start End No. Start End Length (bp)
Lineage 4.8 15 RD219 3,448,504 3,451,396 1 3,448,497 3,451,398 2,902
Lineage 4.1.2.1 12 RD182 2,545,194 2,551,674 1 2,545,195 2,551,675 6,481
    2 2,361,910 2,363,682 1,773
    3 3,194,709 3,194,793 85
    4 4,375,626 4,375,708 83
Lineage 4.3.3 9 RD115 453,364 455,971 1 453,367 455,972 2,606
    2 171,458 171,778 321
    3 2,306,444 2,306,724 281
Lineage 4.1.1.3 9 RD193 2,704,306 2,704,807 1 2,704,310 2,704,806 497
    2 2,339,260 2,339,402 143
Lineage 4.1.1.1 7 RD183 2,585,853 2,588,770 1 2,585,856 2,588,768 2,913
    2 4,370,424 4,373,233 2,810
    3 2,866,744 2,866,852 109
Lineage 4.5 6 RD122 669,793 670,964 1 669,795 670,965 1,171
  1. Note Bold letters emphasize the concordance between exiting RD markers and RDs detected. The start and end positions correspond to the genomic positions of Mtb H37Rv genome