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Table 2 Identification of potential RDs for lineage classification in Mtb lineages with existing RD markers

From: In silico region of difference (RD) analysis of Mycobacterium tuberculosis complex from sequence reads using RD-Analyzer

Lineage

Sample size

Existing RD markers

RD detected

Name

Start

End

No.

Start

End

Length (bp)

Lineage 4.8

15

RD219

3,448,504

3,451,396

1

3,448,497

3,451,398

2,902

Lineage 4.1.2.1

12

RD182

2,545,194

2,551,674

1

2,545,195

2,551,675

6,481

   

2

2,361,910

2,363,682

1,773

   

3

3,194,709

3,194,793

85

   

4

4,375,626

4,375,708

83

Lineage 4.3.3

9

RD115

453,364

455,971

1

453,367

455,972

2,606

   

2

171,458

171,778

321

   

3

2,306,444

2,306,724

281

Lineage 4.1.1.3

9

RD193

2,704,306

2,704,807

1

2,704,310

2,704,806

497

   

2

2,339,260

2,339,402

143

Lineage 4.1.1.1

7

RD183

2,585,853

2,588,770

1

2,585,856

2,588,768

2,913

   

2

4,370,424

4,373,233

2,810

   

3

2,866,744

2,866,852

109

Lineage 4.5

6

RD122

669,793

670,964

1

669,795

670,965

1,171

  1. Note Bold letters emphasize the concordance between exiting RD markers and RDs detected. The start and end positions correspond to the genomic positions of Mtb H37Rv genome