Babesia microti from humans and ticks hold a genomic signature of strong population structure in the United States

Table 2 Summary statistics for polymorphism in apicoplast genomes (28.7 bp)

Statistic	All	Wisconsin	Martha’s Vineyard/Cape Cod	Northeast
No. Samples	25	2	3	20
No. polymorphic (segregating) sites, S	167	42	4	21
No. haplotypes, h	17	2	3	12
Haplotype (gene) diversity, Hd	0.943	1	1	0.911
Std. dev, haplotype diversity	0.031	0.5	0.272	0.045
Nucleotide diversity, Pi	1.14E-03	1.47E-03	9.00E-05	1.60E-04
Std. dev, Pi	3.90E-04	7.30E-04	3.00E-05	2.00E-05
Watterson’s theta (per site)	1.55E-03	1.47E-03	8.00E-05	2.10E-04
Std. dev, Watterson’s theta	5.00E-04	1.10E-06	7.00E-05	8.00E-05
Fu & Li’s D	0.014 §	-	-	−1.219 §
Fu & Li’s F	−0.582 §	-	-	−1.279 §
Tajima’s D	−1.57 §	-	-	−1.567 §

Measures of diversity for all sampled Babesia microti and the three clades identified in the Bayesian phylogeny (Fig. 2). Statistics require sample size > 4 and are therefore not determined for populations from Midwest and Martha’s Vineyard/Cape Cod
§ Fu & Li’s D, Fu & Li’s F and Tajima’s D test statistics are non-significant (p-values > 0.10)

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