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Table 1 CD marker signature defined for BM-MSCs

From: Insights into the human mesenchymal stromal/stem cell identity through integrative transcriptomic profiling

CD identifier

Gene aliases

Description

CD13

ANPEP; PEPN

Aminopeptidase N (Microsomal aminopeptidase) (Gp150)

CD49c

ITGA3

Integrin alpha-3 (Integrin VLA-3 alpha subunit) (Galactoprotein b3)

CD49e

ITGA5; FNRA

Integrin alpha-5 (Integrin VLA-5 alpha subunit) (Fibronectin receptor alpha subunit)

CD58

CD58; LFA3

Lymphocyte function-associated antigen 3 (Surface glycoprotein LFA-3)

CD63

CD63; MLA1

CD63 antigen (Melanoma-associated antigen ME491) (LAMP-3) (Ocular melanoma-associated antigen) (OMA81H) (Granulophysin) (Tetraspanin-30)

CD73

NT5E; NT5; NTE

5′-nucleotidase

CD90

THY1

Thy-1 membrane glycoprotein

CD105

ENG; END

Endoglin

CD107a

LAMP1

Lysosome-associated membrane glycoprotein 1 (LAMP-1)

CD107b

LAMP2

Lysosome-associated membrane glycoprotein 1 (LAMP-2)

CD140b

PDGFRB

Beta-type platelet-derived growth factor receptor (PDGF-R-beta)

CD146

MCAM; MUC18; CD146

Cell surface glycoprotein MUC18 (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12)

CD147

BSG

Basigin (Leukocyte activation antigen M6) (Collagenase stimulatory factor)

CD156c

ADAM10; MADM

ADAM 10 (A disintegrin and metalloproteinase domain 10)

CD164

CD164

Putative mucin core protein 24 (Multi-glycosylated core protein 24)

CD167b

DDR2; NTRKR3

Discoidin domain-containing receptor 2 (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3)

CD213a1

IL13RA1; IL13RA

Interleukin-13 receptor alpha-1 chain

CD222

IGF2R; MPRI

Cation-independent mannose-6-phosphate receptor (Insulin-like growth factor II receptor)

CD230

PRNP

Major prion protein (PrP) (PrP27-30) (PrP33-35C) (ASCR)

CD248

CD248; TEM1

Endosialin (Tumour endothelial marker 1)

CD266

TNFRSF12A; FN14

Tumour necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (Tweak-receptor)

CD280

MRC2; ENDO180

Macrophage mannose receptor 2 (Urokinase receptor-associated protein) (Endocytic receptor 180)

CD284

TLR4

Toll-like receptor 4

CD292

BMPR1A; ACVRLK3

Bone morphogenetic protein receptor type IA (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3)

CD304

NRP1; NRP

Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor)

CD317

BST2

Bone marrow stromal antigen 2 (BST-2)

CD331

FGFR1; FGFBR

Basic fibroblast growth factor receptor 1 (bFGF-R) (Fms-like tyrosine kinase 2)

CDw210b

IL10RB; CRFB4

Interleukin-10 receptor beta chain (IL-10R2) (Cytokine receptor class-II member 4)

  1. Bold font indicates CDs previously reported or used as markers for BM-MSCs (update taken from Calloni’s et al. review [21])