Fig. 2

Metabolic reconstruction of Desulfococcus multivorans for 17 different growth substrates based on combined genomic and differential proteomic data. Assigned proteins are colour coded as follows: grey, genome predicted only; coloured, identified by proteomics (green, 2D DIGE; blue, shotgun analysis; pink, membrane protein-enriched fraction). In case of multiple protein identifications, only one method is indicated hierarchically from 2D DIGE via shotgun analysis down to membrane protein-enriched fraction. Enzyme names and their predicted functions are provided in Additional file 1: Table S1. Putative and assumed routes of electron flow are indicated by dashed lines. Compound names: (1) acetate, (2) 2-hydroxybenzoate, (3) benzoate, (4) 3-phenylpropanoate (hydrocinnamate), (5) cinnamate, (6) phenylacetate, (7) phenylpyruvate, (8) cyclohexane carboxylate, (9) 3-methylbutanoate, (10) myristinate, (11) butanoate, (12) n-butanol, (13) isobutanoate, (14) 2-methylbutanoate, (15) propanoate, (16) 1-propanol, and (17) lactate