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Table 6 The top 10 KEGG pathways for cold-related genes

From: MicroRNAs regulate gene plasticity during cold shock in zebrafish larvae

KEGG pathway of

P value*

Cold-induced genes

 MAPK signaling pathway

2.60E-05

 Circadian rhythm

2.60E-04

 RIG-I-like receptor signaling pathway

0.011

 GnRH signaling pathway

0.025

 Cell adhesion molecules (CAMs)

0.026

 Adherens junction

0.034

 Melanogenesis

0.036

 Hedgehog signaling pathway

0.049

 NOD-like receptor signaling pathway

0.056

 Insulin signaling pathway

0.057

Cold-repressed genes

 Neuroactive ligand-receptor interaction

3.90E-03

 Steroid biosynthesis

6.50E-03

  1. *calculated by Fisher Exact which is adopted to measure the gene-enrichment in annotation KEGG pathway
  2. The cold-related genes (Additional file 6) were annotated by DAVID bioinformatics resources 6.7. The top 10 KEGG pathway of the genes and P values are shown
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BMC Genomics

ISSN: 1471-2164

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