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Table 3 Model fitting results for strategy (A) CoxLasso, (B) CoxSis and (C) CoxSisLasso

From: Exploring the key genes and signaling transduction pathways related to the survival time of glioblastoma multiforme patients by a novel survival analysis model

Key genes

coef

exp(coef)

se(coef)

z

p-value

A

ARIH2

0.28827

1.33412

0.20957

1.376

0.1690

ZNF786

0.73967

2.09524

0.31849

2.322

0.0202*

AEBP1

0.09910

1.10418

0.09315

1.064

0.2874

FOXG1

0.14722

1.15861

0.06712

2.193

0.0283*

INTS1

0.19661

1.21726

0.27385

0.718

0.4728

GDNF

−0.33054

0.71854

0.29059

−1.137

0.2553

CUTC

−0.03165

0.96885

0.27837

−0.114

0.9095

SGCD

0.12861

1.13724

0.20752

0.620

0.5354

CCM2

0.29707

1.34591

0.28104

1.057

0.2905

IL17RC

0.51024

1.66569

0.21579

2.364

0.0181*

EIF3A

−0.27131

0.76238

0.23337

−1.163

0.2450

CBLN1

−0.29685

0.74316

0.30079

−0.987

0.3237

R2 = 0.338, Concordance = 0.687

B

YAP1

−0.28804

0.74973

0.12372

−2.328

0.019902*

TRAF3IP2

−0.39514

0.67358

0.20318

−1.945

0.051805

AEBP1

0.33103

1.39239

0.09268

3.572

0.000354***

GDNF

−1.09305

0.33519

0.30549

−3.578

0.000346***

EAF2

−0.53363

0.58647

0.21472

−2.485

0.012949*

ST5

−0.26305

0.76870

0.26139

−1.006

0.314240

IL17RC

1.02690

2.79240

0.22954

4.474

7.69e-06***

EIF3A

−0.40494

0.66702

0.21963

−1.844

0.065216

R2 = 0.375, Concordance = 0.696

C

ARIH2

0.27310

1.31403

0.20654

1.322

0.186080

ZNF786

1.17873

3.25025

0.31923

3.692

0.000222***

AEBP1

0.20724

1.23027

0.09558

2.168

0.030151*

FOXG1

0.32694

1.38672

0.09262

3.530

0.000416***

INTS1

0.85607

2.35388

0.34015

2.517

0.011844*

GDNF

−0.48393

0.61636

0.35170

−1.376

0.168835

SGCD

−0.53359

0.58650

0.22601

−2.361

0.018233*

IL17RC

1.23644

3.44332

0.23552

5.250

1.52e-07***

EIF3A

−0.08224

0.92105

0.22885

−0.359

0.719339

CBLN1

−1.06495

0.34474

0.38400

−2.773

0.005548**

SLC35D1

−0.44547

0.64052

0.21196

−2.102

0.035579*

ELOVL2

−0.16161

0.85077

0.08395

−1.925

0.054210

CDCA7L

−0.38939

0.67747

0.11097

−3.509

0.000450***

SNTB1

−0.61372

0.54133

0.16747

−3.665

0.000248***

TELO2

−1.28721

0.27604

0.48148

−2.673

0.007507**

R2 = 0.515, Concordance = 0.747

  1. Significance codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05
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BMC Genomics

ISSN: 1471-2164

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