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Table 3 Model fitting results for strategy (A) CoxLasso, (B) CoxSis and (C) CoxSisLasso

From: Exploring the key genes and signaling transduction pathways related to the survival time of glioblastoma multiforme patients by a novel survival analysis model

Key genes coef exp(coef) se(coef) z p-value
A
ARIH2 0.28827 1.33412 0.20957 1.376 0.1690
ZNF786 0.73967 2.09524 0.31849 2.322 0.0202*
AEBP1 0.09910 1.10418 0.09315 1.064 0.2874
FOXG1 0.14722 1.15861 0.06712 2.193 0.0283*
INTS1 0.19661 1.21726 0.27385 0.718 0.4728
GDNF −0.33054 0.71854 0.29059 −1.137 0.2553
CUTC −0.03165 0.96885 0.27837 −0.114 0.9095
SGCD 0.12861 1.13724 0.20752 0.620 0.5354
CCM2 0.29707 1.34591 0.28104 1.057 0.2905
IL17RC 0.51024 1.66569 0.21579 2.364 0.0181*
EIF3A −0.27131 0.76238 0.23337 −1.163 0.2450
CBLN1 −0.29685 0.74316 0.30079 −0.987 0.3237
R2 = 0.338, Concordance = 0.687
B
YAP1 −0.28804 0.74973 0.12372 −2.328 0.019902*
TRAF3IP2 −0.39514 0.67358 0.20318 −1.945 0.051805
AEBP1 0.33103 1.39239 0.09268 3.572 0.000354***
GDNF −1.09305 0.33519 0.30549 −3.578 0.000346***
EAF2 −0.53363 0.58647 0.21472 −2.485 0.012949*
ST5 −0.26305 0.76870 0.26139 −1.006 0.314240
IL17RC 1.02690 2.79240 0.22954 4.474 7.69e-06***
EIF3A −0.40494 0.66702 0.21963 −1.844 0.065216
R2 = 0.375, Concordance = 0.696
C
ARIH2 0.27310 1.31403 0.20654 1.322 0.186080
ZNF786 1.17873 3.25025 0.31923 3.692 0.000222***
AEBP1 0.20724 1.23027 0.09558 2.168 0.030151*
FOXG1 0.32694 1.38672 0.09262 3.530 0.000416***
INTS1 0.85607 2.35388 0.34015 2.517 0.011844*
GDNF −0.48393 0.61636 0.35170 −1.376 0.168835
SGCD −0.53359 0.58650 0.22601 −2.361 0.018233*
IL17RC 1.23644 3.44332 0.23552 5.250 1.52e-07***
EIF3A −0.08224 0.92105 0.22885 −0.359 0.719339
CBLN1 −1.06495 0.34474 0.38400 −2.773 0.005548**
SLC35D1 −0.44547 0.64052 0.21196 −2.102 0.035579*
ELOVL2 −0.16161 0.85077 0.08395 −1.925 0.054210
CDCA7L −0.38939 0.67747 0.11097 −3.509 0.000450***
SNTB1 −0.61372 0.54133 0.16747 −3.665 0.000248***
TELO2 −1.28721 0.27604 0.48148 −2.673 0.007507**
R2 = 0.515, Concordance = 0.747
  1. Significance codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05