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Table 4 Comparisons of tools that utilized Connectivity Map concept

From: DeSigN: connecting gene expression with therapeutics for drug repurposing and development

Tools

Relationship feature

Reference database

DeSigN

Global baseline DEGs to drug response

GDSC

NFFinder

Transcriptomic data to drugs, diseases and experts

GEO, CMap and DrugMatrix

DMAP

Protein/gene to drug response

STITCH and HAPPI

FMCM

Pre- and post-treatment gene expression to drug response

CMap