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Fig. 6 | BMC Genomics

Fig. 6

From: CORALINA: a universal method for the generation of gRNA libraries for CRISPR-based screening

Fig. 6

Visual representation of protospacer alignments to a ribosomal gene unit. Shown are sequences detected in the sequencing reads of three human CORALINA libraries (L1, L2, L3) which correspond to a ribosomal gene unit on chromosome 21. Alignments to the positive DNA strands are shown above, those to the negative DNA strand below the gene structure using the UCSC genome browser (blue from left to right: 5′ETS, ITSs, 3′ETS; orange: 18S rRNA, 5.8S rRNA, 28S rRNA)

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