Fig. 3
From: Genome-wide analysis of G-quadruplexes in herpesvirus genomes
Regulatory regions of herpesvirus genomes have higher PQS densities. a PQS are enriched in regulatory regions as compared to coding regions: Bar graphs showing significant enrichment of PQS densities in the regulatory regions (i.e., 1000bp upstream of the start codon) as compared to that in coding regions. The number of full-length sequences studied for each virus is shown in parentheses. b GC content of regulatory regions is lower than that of the coding regions in herpesvirus genomes. c Native regulatory regions within herpesvirus genomes have significantly higher PQS densities compared to randomly generated regulatory regions within herpesvirus genomes. Each regulatory region within a herpesvirus genome was randomized 5 times. The fold change between average PQS density of native regulatory region and average PQS density of randomized regulatory regions is plotted. * denotes P < 0.05