Fig. 1

Phylogenomic analyses of 142 cyanophages. a Unrooted phylogenomic maximum likelihood tree of 51 concatenated core genes (see Additional file 2: Table S2) in 142 genome-sequenced isolates reveals 10 distinct cyanophage genomic lineages. Six lineages (designated I-VI) contain three or more representatives, while the remaining four are less well-represented and indicated by colored hexagons. Isolate origin (coastal = white or offshore = black) is designated in the outer ring. b Pairwise comparisons of average nucleotide identity (ANI) of shared genes between genomes in the well-represented lineages reveals six with ANI >98% that correspond to phylogenomic clusters I-VI. (C) The pairwise fraction of shared genes within clusters are high (>96%). Clustering of ANI and shared gene content are statistically not random (Additional file 2: Table S6) and correspond to bootstrapped phylogenomic lineages