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Table 3 The most enriched GO terms of differentially expressed genes in the three tissues

From: Transcriptome analysis reveals the genetic basis underlying the seasonal development of keratinized nuptial spines in Leptobrachium boringii

Go term P-value DEG (all) Representative genes
(a) Upper jaw skin: differentially expressed genes: 1181
 Cytosolic part
<0.001 17 (148) Rab interacting lysosomal protein; keratin, type I cytoskeletal 42-like; keratin 17; dystrophin related protein 2
 Peptidase inhibitor activity (GO:0030414:MF) <0.001 20 (232) Collagen alpha-1(XXVIII) chain; Cathelicidin antimicrobial peptide; small nuclear ribonucleoprotein polypeptide A; serpin B5
 Peptidase regulator activity GO:0061134:MF) <0.001 20 (234) Cystatin B (stefin B); tectorin alpha, gene 2 precursor; cystatin-like isoform 1; WAP four-disulfide core domain protein 3-like
 Extracellular region part
<0.001 49 (786) Keratin 17; newt-specific cysteine-rich growth regulator; keratin, type II cytoskeletal 75-like; extracellular matrix protein 1 isoform 1
 Prefoldin complex
<0.001 11 (71) Keratin, type I cytoskeletal 42-like; keratin 17;keratin, type I cytoskeletal 18-B; dystrophin related protein 2
 Extracellular region (GO:0005576:CC) <0.001 95 (1993) Keratin 17; insulin-like growth factor-binding protein 2 precursor; transmembrane protein 111
(b) Testis: differentially expressed genes: 843
<0.001 51 (627) Origin recognition complex, subunit 1; shugoshin-like protein 2; ubiquitin-conjugating enzyme E2 T
 Chromosomal part (GO:0044427:CC) <0.001 45 (538) Tryptophan rich basic protein precursor; centromere protein I; proliferating cell nuclear antigen
<0.001 26 (194) DNA replication licensing factor mcm4; GTP-binding nuclear protein Ran; transcriptional activator Myb isoform 2
 Cell cycle
<0.001 50 (711) Meiotic nuclear divisions 1 homolog; proliferating cell nuclear antigen; cyclin-dependent kinases regulatory subunit 2
 MCM complex
<0.001 6 (10) DNA replication licensing factor mcm5; DNA replication licensing factor mcm4; zygotic DNA replication licensing factor mcm6
 Chromatin binding
<0.001 17 (131) High mobility group nucleosomal binding domain 3; DNA replication licensing factor mcm4; transcriptional activator Myb isoform 2
(c) Brain: differentially expressed genes: 107
 Aralkylamine N-acetyltransferase activity (GO:0004059:MF) 0.002 1 (1) Arylalkylamine N-acetyltransferase;
 Selenium binding (GO:0008430:MF) 0.003 2 (41) Selenoprotein P, plasma, 1-like precursor;
 Sulfonylurea receptor activity (GO:0008281:MF) 0.004 1(2) ATP-binding cassette sub-family C member 9 isoform 1;
 Actin crosslink formation
0.009 1 (5) Actinin, alpha 3
 Cysteine-type peptidase activity
0.009 3 (241) Cthepsin K-like; cathepsin L1 precursor;
 Protein-hormone receptor activity
0.014 1 (8) Thyrotropin receptor isoform 1 precursor
  1. The significantly enriched GO terms in each tissue of Leptobrachium boringii are presented above. For each GO term, its ID, the ontology of level 1 (BP, Biological Process; MF, Molecular Function; CC, Cellular Component), count of the number of differentially expressed genes (DEGs) and the number of all annotated genes are presented (All in brackets). The representative genes of each enriched GO term are also provided here