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Table 4 Significantly enriched KEGG pathways among differentially expressed genes in Leptobrachium boringii

From: Transcriptome analysis reveals the genetic basis underlying the seasonal development of keratinized nuptial spines in Leptobrachium boringii

Tissue DEGs type Pathway FDR DEGs All genes
Spine All Glycolysis/Gluconeogenesis 1.65E-02 14 87
Up-regulated Ribosome biogenesis in eukaryotes 7.88E-04 10 70
Biosynthesis of secondary metabolites 3.12E-03 22 360
Proteasome 1.68E-02 6 40
Sulfur relay system 3.97E-02 3 9
Pentose phosphate pathway 4.08E-02 5 35
Aminoacyl-tRNA biosynthesis 4.40E-02 5 37
Down-regulated Retinol metabolism 8.78E-04 12 91
ECM-receptor interaction 4.19E-03 11 98
Tyrosine metabolism 4.19E-03 8 53
Drug metabolism - cytochrome P450 1.20E-02 10 98
Glycolysis / Gluconeogenesis 1.52E-02 9 87
Nicotinate and nicotinamide metabolism 1.52E-02 6 39
Vitamin B6 metabolism 2.30E-02 3 8
Pantothenate and CoA biosynthesis 2.39E-02 4 18
Testis All Cell cycle 3.29E-11 27 125
DNA replication 9.73E-11 14 30
Cell cycle - yeast 1.38E-10 20 73
Meiosis - yeast 4.89E-05 12 56
Mismatch repair 5.80E-05 7 17
Pyrimidine metabolism 5.76E-04 14 97
Fanconi anemia pathway 3.52E-03 8 41
Homologous recombination 5.07E-03 6 24
Purine metabolism 1.78E-02 17 187
Down-regulated Cell cycle 0.00E + 00 26 125
DNA replication 1.67E-13 14 30
Cell cycle - yeast 3.46E-13 19 73
Meiosis - yeast 3.19E-07 12 56
Mismatch repair 2.53E-06 7 17
Pyrimidine metabolism 1.11E-04 12 97
Fanconi anemia pathway 1.29E-04 8 41
Homologous recombination 3.89E-04 6 24
Base excision repair 1.57E-02 5 31
Nucleotide excision repair 2.18E-02 5 34
Spliceosome 2.31E-02 10 133
Oocyte meiosis 2.31E-02 9 112
Purine metabolism 2.74E-02 12 187
p53 signaling pathway 4.31E-02 6 61
  1. The significantly enriched KEGG pathways in each tissue of Leptobrachium boringii are presented above. FDR represent the false discovery rate adjusted P-value. For each enriched KEGG pathway, we counted the number of differentially expressed genes (DEGs) and the number of all annotated genes (All in brackets). Spine represents the upper jaw skin