Table 1 Genes differentially methylated in newborns in relation to maternal smoking during pregnancy using the Sequence Kernel Association Test (SKAT) in the MoBa1 discovery cohort (n = 1062 subjects)
Genea | Markers/Gene | SKAT p-value | SKAT q-value |
|---|---|---|---|
GFI1 | 71 | 1.05E-17 | 2.13E-13 |
MYO1G | 12 | 4.33E-17 | 4.37E-13 |
CYP1A1 | 35 | 1.21E-09 | 8.15E-06 |
RUNX1 | 53 | 3.46E-07 | 0.001749 |
LCTL | 8 | 1.61E-05 | 0.065098 |
AHRR | 149 | 6.29E-05 | 0.184672 |
FCRLA | 9 | 8.14E-05 | 0.184672 |
MIR641 | 4 | 8.23E-05 | 0.184672 |
TRAK1 | 35 | 7.78E-05 | 0.184672 |
C1ORF180 | 4 | 0.000104 | 0.209611 |
ITLN2 | 5 | 0.000116 | 0.212334 |
GLIS1 | 51 | 0.000156 | 0.223673 |
LRFN1 | 21 | 0.00016 | 0.223673 |
MIR451 | 8 | 0.000166 | 0.223673 |
SLC25A24 | 23 | 0.000144 | 0.223673 |