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Table 3 Loss of coordinated COP9 gene expression in HNSCC

From: Analysis of RNA expression of normal and cancer tissues reveals high correlation of COP9 gene expression with respiratory chain complex components

Normal vs. Tumor (paired 42)
Normal GPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS8
 GPS1 1 −0.059 0.303 0.369 0.385 0.75 0.522 0.519
 COPS2 −0.059 1 0.783 0.676 0.683 0.072 0.587 0.415
 COPS3 0.303 0.783 1 0.775 0.841 0.536 0.777 0.465
 COPS4 0.369 0.676 0.775 1 0.786 0.369 0.797 0.835
 COPS5 0.385 0.683 0.841 0.786 1 0.521 0.843 0.618
 p 0.012 6.25E-07 3.30E-12 6.90E-10 - 4.09E-04 2.37E-12 1.32E-05
 COPS6 0.75 0.072 0.536 0.369 0.521 1 0.479 0.296
 COPS7A 0.522 0.587 0.777 0.797 0.843 0.479 1 0.675
 COPS8 0.519 0.415 0.465 0.835 0.618 0.296 0.675 1
Tumor GPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS8
 GPS1 1.000 −0.091 0.055 0.012 0.212 0.360 −0.195 0.218
 COPS2 −0.091 1.000 0.126 −0.073 0.218 −0.271 −0.029 −0.066
 COPS3 0.055 0.126 1.000 0.043 0.033 0.342 −0.213 0.258
 COPS4 0.012 −0.073 0.043 1.000 0.024 −0.023 0.300 0.066
 COPS5 0.212 0.218 0.033 0.024 1.000 −0.053 −0.196 0.244
 p 0.177 0.165 0.836 0.88 - 0.741 0.213 0.12
 COPS6 0.360 −0.271 0.342 −0.023 −0.053 1.000 −0.041 0.205
 COPS7A −0.195 −0.029 −0.213 0.300 −0.196 −0.041 1.000 −0.197
 COPS8 0.218 −0.066 0.258 0.066 0.244 0.205 −0.197 1.000
  1. Normal and matched HNSCC tissues (sample number = 42) were compared for their correlation coefficient values among the COP9 genes
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BMC Genomics

ISSN: 1471-2164

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