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Table 7 Synchronized expression of the COP9 genes in the matched tissues of normal and lung squamous cell carcinoma

From: Analysis of RNA expression of normal and cancer tissues reveals high correlation of COP9 gene expression with respiratory chain complex components

Correlation Coefficient among COP9 genes, Lung Squamous Cell Carcinoma (n = 50)
Normal GPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8
 GPS1 1.000 −0.092 0.268 0.269 0.278 0.717 0.781 0.194 0.244
 COPS2 −0.092 1.000 0.792 0.844 0.742 0.300 0.193 −0.432 0.725
 COPS3 0.268 0.792 1.000 0.910 0.859 0.557 0.455 −0.373 0.837
 COPS4 0.269 0.844 0.910 1.000 0.909 0.603 0.524 −0.279 0.910
 COPS5 0.278 0.742 0.859 0.909 1.000 0.550 0.497 −0.141 0.859
 p 0.051 6.85E-10 1.33E-15 0.00E + 00 - 3.49E-05 2.40E-04 0.329 1.55E-15
 COPS6 0.717 0.300 0.557 0.603 0.550 1.000 0.716 −0.009 0.602
 COPS7A 0.781 0.193 0.455 0.524 0.497 0.716 1.000 0.197 0.461
 COPS7B 0.194 −0.432 −0.373 −0.279 −0.141 −0.009 0.197 1.000 −0.257
 COPS8 0.244 0.725 0.837 0.910 0.859 0.602 0.461 −0.257 1.000
Tumor GPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8
 GPS1 1.000 0.059 0.261 0.228 0.109 0.529 0.307 0.304 0.193
 COPS2 0.059 1.000 0.413 0.488 0.142 0.105 0.143 −0.180 0.207
 COPS3 0.261 0.413 1.000 0.240 0.267 0.466 0.320 −0.075 0.137
 COPS4 0.228 0.488 0.240 1.000 0.235 0.082 0.023 0.076 0.177
 COPS5 0.109 0.142 0.267 0.235 1.000 0.233 0.103 0.212 0.170
 p 0.452 0.326 0.061 0.101 - 0.103 0.477 0.139 0.239
 COPS6 0.529 0.105 0.466 0.082 0.233 1.000 0.640 0.120 0.180
 COPS7A 0.307 0.143 0.320 0.023 0.103 0.640 1.000 −0.094 0.008
 COPS7B 0.304 −0.180 −0.075 0.076 0.212 0.120 −0.094 1.000 0.613
 COPS8 0.193 0.207 0.137 0.177 0.170 0.180 0.008 0.613 1.000
  1. The analysis was carried out in the same way as for Table 3. Values in bold letters indicate significantly high COSP5 correlation with other COP9 components