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Fig. 1 | BMC Genomics

Fig. 1

From: Genome-wide map of RNA degradation kinetics patterns in dendritic cells after LPS stimulation facilitates identification of primary sequence and secondary structure motifs in mRNAs

Fig. 1

Pattern classification of degradation kinetics. a Scheme for classification of degradation patterns. Each gene has 8 time points after LPS stimulation, and 5 time points after ActD addition are associated with each LPS time points. At the first step, these time course data after LPS addition are clustered (Step 1). On the second step degradation rates for each clusters are calculated (Step 2), then assigned the ranks to each genes at each time points after LPS stimulation (Step 3). b Time course data classified as long-lived or short-lived. Degradation time course and their means (in bold line) were plotted. c Heat map image of the resulting clusters. Obtained 16 clusters are indicated by side colors. The clusters are ordered from quickest degradation to slowest from top to bottom. Only cluster cores are shown. d Degradation of mRNAs after ActD addition (left panels) and rank of degradation rates at each time points after LPS addition (right panels) are shown for each genes

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