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Table 1 Genomic features of Cryptosporidium ubiquitum and C. andersoni in comparison with other apicomplexan parasitesa

From: Evolution of mitosome metabolism and invasion-related proteins in Cryptosporidium

  P. falciparum T. gondii C. parvum C. hominis C. ubiquitum C. andersoni
Total length (Mb) 22.85 65.67 9.10 8.74 8.97 9.09
No. of super contigs 16 2,263 8 1,422 27 135
GC content (%) 20.0 48.5 30.3 30.9 30.8 28.5
No. of genes 5,542 8,322 3,805 3,886 3,767 3,905
Total length of CDS (Mb)b 12.58 20.03 6.83 5.28 6.94 6.86
GC content in CDS (%) 25.0 56.0 31.9 32.7 33.0 30.1
GC content at 3rd position in codons (%) 18.0 59.0 18.0 19.0 20.0 14.0
Mean length of genes (bp) 2,271 2,407 1,720 1,360 1,841 1,757
Gene density (gene/Mb) 242.5 126.7 418.1 444.6 420.0 429.6
Percent coding (%) 55.1 30.5 75.0 60.4 77.4 75.5
No. of genes with intron 3,055 6,729 163 8 758 832
Genes with intron (%) 55.1 80.9 4.2 0.02c 20.1 21.3
No. of tRNA 72 174 45 46 45 44
No. of tRNAmet 2 8 2 2 2 2
Proteins with signal peptide 638 759 397 421 399 309
Proteins with transmembrane domain 1,754 1,103 832 769 772 839
Proteins with GPI anchor 62 255 63 51 50 47
  1. aSource of data: Plasmodium falciparum: PlasmoDB release-11.1; Toxoplasma gondii: ToxoDB release-11.0; C. parvum and C. hominis: CryptoDB release-6.0
  2. bCoding regions excluding intron sequences
  3. cEstimated to be 5–20% by Xu et al., [4]