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Fig. 2 | BMC Genomics

Fig. 2

From: Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence

Fig. 2

Hierarchically compiled output of an analysis for master regulators orchestrating gene expression program executed in replicative senescence. Stromelysin, the master regulator of this network, is highlighted in red, intermediate controllers that are added by GeneXPlain algorithm, a subset of input molecules is highlighted in blue. The intensity of the pink/red bars on a side of the molecule box represents the degree of overexpression for respective genes

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