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Table 3 Transcription factor genes differentially expressed in ISIAH and WAG adrenal glands

From: Molecular determinants of the adrenal gland functioning related to stress-sensitive hypertension in ISIAH rats

Gene symbol

Gene_ID

log2 (fold_change) ISIAH/WAG

Gene definition

Ajuba

85265

1.22

ajuba LIM protein

Apbb1

29722

0.52

amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)

Arhgap5

299012

−0.58

Rho GTPase activating protein 5

Bcl6

303836

−1.16

B-cell CLL/lymphoma 6

Cbfb

361391

−0.66

core-binding factor, beta subunit

Ccnc

114839

−0.59

cyclin C

Ccnl2

298686

−0.72

cyclin L2

Cebpa

24252

0.85

CCAAT/enhancer binding protein (C/EBP), alpha

Cnot3

308311

0.60

CCR4-NOT transcription complex, subunit 3

Creb3l1

362165

1.22

cAMP responsive element binding protein 3-like 1

Csrp2

29317

−0.60

cysteine and glycine-rich protein 2

Dab2

79128

0.79

disabled homolog 2 (Drosophila)

Egr1 a

24330

−0.92

early growth response 1

Ets2

304063

−0.83

v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Etv1

362733

−0.52

ets variant 1

Fev

246271

−0.92

FEV (ETS oncogene family)

Foxo1 b

84482

−0.86

forkhead box O1

Fus

317385

0.65

fused in sarcoma

Grhl1

313993

1.06

grainyhead-like 1 (Drosophila)

Hcls1

288077

0.63

hematopoietic cell specific Lyn substrate 1

Hdac4 a

363287

0.73

histone deacetylase 4

Hes1

29577

−0.84

hairy and enhancer of split 1 (Drosophila)

Hltf

295568

−0.58

helicase-like transcription factor

Ifi204

304988

1.05

interferon activated gene 204

Irf7

293624

1.64

interferon regulatory factor 7

Irf9

305896

0.77

interferon regulatory factor 9

Junb

24517

−1.58

jun B proto-oncogene

Klhl6

287974

1.00

kelch-like family member 6

Lcor

365462

−0.59

ligand dependent nuclear receptor corepressor

Ldb3

498587

1.30

LIM domain binding 3

Mbd1

291439

−0.81

methyl-CpG binding domain protein 1

Mcm7

288532

0.80

minichromosome maintenance complex component 7

Mlxipl

171078

−0.93

MLX interacting protein-like

Mphosph8

290270

−0.86

M-phase phosphoprotein 8

Nfkbil1

361794

0.62

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

Nfx1

313166

0.50

nuclear transcription factor, X-box binding 1

Nkx3-1

305999

2.11

NK3 homeobox 1

Nr1d1

252917

−0.57

nuclear receptor subfamily 1, group D, member 1

Nr4a3

58853

1.20

nuclear receptor subfamily 4, group A, member 3

Nrip1

304157

−0.70

nuclear receptor interacting protein 1

Pcaf

301164

−0.54

p300/CBP-associated factor

Pdlim3

114108

1.06

PDZ and LIM domain 3

Pml

315713

0.54

promyelocytic leukemia

Ppard b

25682

0.56

peroxisome proliferator-activated receptor delta

Pparg a b

25664

1.01

peroxisome proliferator-activated receptor gamma

Preb

58842

0.52

prolactin regulatory element binding

Pric285

296474

0.50

peroxisomal proliferator-activated receptor A interacting complex 285

Prpf4b

291078

−0.58

PRP4 pre-mRNA processing factor 4 homolog B (yeast)

Rbm43

311020

0.80

RNA-binding protein 43

Rere

116665

−0.57

arginine-glutamic acid dipeptide (RE) repeats

Smurf2

303614

0.95

SMAD specific E3 ubiquitin protein ligase 2

Stat5b

25126

−0.50

signal transducer and activator of transcription 5B

Tcf3

171046

0.67

transcription factor 3

Tfdp2

300947

−0.78

transcription factor Dp-2 (E2F dimerization partner 2)

Tgfb1i1

84574

1.11

transforming growth factor beta 1 induced transcript 1

Twist2

59327

1.00

twist homolog 2 (Drosophila)

Vgll3

498038

1.66

vestigial-like family member 3

Zbtb16

353227

1.26

zinc finger and BTB domain containing 16

Zfp281

305083

−0.54

zinc finger protein 281

Zfp292

50552

−0.53

zinc finger protein 292

Zmynd12

313552

−0.96

zinc finger, MYND-type containing 12

  1. Genes associated with: a- hypertension; b - insulin resistance; ISIAH and WAG – rat strains used in the study