Table 4 The top 10 DEGs making the most significant contribution to the inter-strain differences and associated with hypertension
Gene symbol | Gene_ID | log2 (fold_change) ISIAH/WAG | Gene definition |
|---|---|---|---|
Agt | 24179 | 2.28 | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
Avpr1a | 25107 | 1.12 | arginine vasopressin receptor 1A |
Ephx2 | 65030 | 4.37 | epoxide hydrolase 2, cytoplasmic |
Gabbr1 | 81657 | 1.11 | gamma-aminobutyric acid (GABA) B receptor 1 |
Hsd11b2 | 25117 | −1.47 | hydroxysteroid 11-beta dehydrogenase 2 |
Igf1 | 24482 | −2.12 | insulin-like growth factor 1 |
Mpo | 303413 | 4.46 | myeloperoxidase |
S100b | 25742 | −1.72 | S100 calcium binding protein B |
Serpine1 | 24617 | −2.04 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
Serpine2 | 29366 | 2.19 | serpin peptidase inhibitor, clade E, member 2 |