| | |
RMC
|
RMC
|
|---|
|
Line
|
Metabolite
|
SDF
|
(se)
|
SDS
|
(se)
|
|---|
|
IL3-2
|
Lactate
|
1.263
|
(0.17)
|
0.444
|
(0.04)*
|
|
Isoleucine
|
1.123
|
(0.05)
|
0.683
|
(0.03)**
|
|
Valine
|
1.384
|
(0.25)
|
0.439
|
(0.06)*
|
|
Methionine
|
1.321
|
(0.21)
|
0.265
|
(0.06)*
|
|
Aspartate
|
0.522
|
(0.07)
|
1.804
|
(0.1)**
|
|
2OH glutarate
|
2.728
|
(0.78)
|
0.510
|
(0.12)*
|
|
4OH benzoate
|
1.265
|
(0.17)
|
0.476
|
(0.06)*
|
|
Arginine
|
1.646
|
(0.44)
|
0.417
|
(0.02)*
|
|
Fructose
|
0.837
|
(0.11)
|
0.343
|
(0.03)*
|
|
Lysine
|
0.976
|
(0.17)
|
0.343
|
(0.05)*
|
|
M82
|
MMP
|
1.305
|
(0.18)
|
0.632
|
(0.1)*
|
|
Methionine
|
0.817
|
(0.12)
|
1.257
|
(0.12)*
|
|
GABA
|
0.842
|
(0.09)
|
1.292
|
(0.08)***
|
|
Cysteine
|
0.850
|
(0.08)
|
1.294
|
(0.1)**
|
|
Asparagine
|
0.863
|
(0.08)
|
1.143
|
(0.07)**
|
|
Ferulate
|
0.767
|
(0.06)
|
1.429
|
(0.15)***
|
|
IL2-1
|
Nicotinate
|
0.642
|
(0.06)
|
1.206
|
(0.11)*
|
|
GABA
|
1.017
|
(0.21)
|
0.267
|
(0.07)*
|
|
Alloinositol
|
0.730
|
(0.06)
|
1.149
|
(0.07)*
|
|
Dopamine
|
0.570
|
(0.1)
|
1.898
|
(0.15)*
|
|
IL2-4
|
Glycerate
|
0.715
|
(0.2)
|
2.520
|
(0.15)*
|
|
Fumarate
|
0.854
|
(0.16)
|
3.347
|
(0.45)*
|
|
Alloinositol
|
1.767
|
(0.24)
|
0.528
|
(0)*
|
|
IL12-3
|
2OH glutarate
|
0.611
|
(0.06)
|
1.192
|
(0.09)**
|
|
Fructose
|
0.472
|
(0.14)
|
1.953
|
(0.17)*
|
|
Glucose
|
0.567
|
(0.09)
|
1.780
|
(0.18)**
|
|
IL3-1
|
Succinate
|
0.520
|
(0.07)
|
1.143
|
(0.12)*
|
|
2OH glutarate
|
0.534
|
(0.05)
|
1.598
|
(0.25)*
|
|
IL7-1
|
Glycerol
|
0.355
|
(0.07)
|
0.968
|
(0.25)*
|
|
Saccharate
|
1.263
|
(0.13)
|
0.579
|
(0.18)*
|
|
IL7-5
|
Tartarate
|
0.730
|
(0.16)
|
1.777
|
(0.24)*
|
|
Saccharate
|
1.378
|
(0.07)
|
0.655
|
(0.15)*
|
|
IL1-1
|
Citrate
|
0.184
|
(0.03)
|
1.145
|
(0.2)*
|
|
IL1-1-3
|
Isoleucine
|
1.190
|
(0.08)
|
0.707
|
(0.07)*
|
|
IL1-3
|
Gluconate
|
1.082
|
(0.11)
|
1.864
|
(0.1)*
|
|
IL1-4
|
Glycerol 2 phosphate
|
0.564
|
(0.03)
|
0.873
|
(0.06)*
|
|
IL2-3
|
Tryptamine
|
2.284
|
(0.3)
|
1.072
|
(0.06)*
|
|
IL3-4
|
Aspartate
|
0.686
|
(0.09)
|
1.767
|
(0.27)*
|
|
IL3-5
|
Tyramine
|
0.965
|
(0.19)
|
0.189
|
(0.24)*
|
|
IL4-1-1
|
Arabinose
|
0.471
|
(0.04)
|
1.151
|
(0.18)*
|
|
IL4-2
|
Dopamine
|
0.879
|
(0.2)
|
0.199
|
(0.33)*
|
|
IL4-3-2
|
Galactarate
|
0.559
|
(0.04)
|
1.022
|
(0.58)*
|
|
IL5-3
|
Cysteine
|
2.114
|
(0.12)
|
1.092
|
(0)*
|
|
IL6-4
|
Arabinose
|
0.307
|
(0.06)
|
0.774
|
(0.42)*
|
|
IL7-3
|
Dopamine
|
3.641
|
(1.01)
|
0.636
|
(0.93)*
|
|
IL7-4-1
|
Sorbitol
|
0.231
|
(0.03)
|
1.143
|
(0.12)**
|
|
IL9-1
|
Alanine
|
0.476
|
(0.06)
|
0.935
|
(0.44)*
|
|
IL9-3
|
Glucose
|
2.714
|
(0.03)
|
0.628
|
(0.35)*
|
|
IL9-3-1
|
Arginine
|
1.832
|
(0.26)
|
0.864
|
(0.13)*
|
|
IL11-1
|
Fructose
|
0.277
|
(0.02)
|
0.497
|
(0.03)**
|
|
IL11-4-1
|
Glycerol
|
1.432
|
(0.17)
|
0.475
|
(0.09)**
|
|
IL12-2
|
Alanine
|
0.415
|
(0.05)
|
0.875
|
(0.05)*
|
|
IL12-4
|
Lactate
|
0.484
|
(0.05)
|
1.315
|
(0.19)*
|
- The average RMC and standard error (se) in SDS and SDF for lines in which there was a significant difference between treatments
- Asterisks mark significant differences between treatments of *
p < 0.01, **
p < 0.001, ***
p < 0.0001
