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Table 1 The genes with the strongest membership with the top two LPS-related modules

From: LPS-induced modules of co-expressed genes in equine peripheral blood mononuclear cells

Module

Module hub genes

Module membership

LPS log2FC

DE FDR

module I

BIRC3

0.97

1.26

1.89e-12

module I

VPS37A

0.95

0.53

3.97e-9

module I

STARD13

0.94

0.80

1.01e-4

module I

SOD2

0.94

1.75

8.83e-16

module I

SLC1A2

0.94

2.83

3.62e-18

module I

ARHGEF3

0.94

0.53

3.39e-8

module I

TTC25

0.94

0.84

5.30e-8

module I

SLC39A14

0.93

1.80

2.80e-12

module I

ENSECAG00000002023, superoxide dismutase

0.93

1.79

5.69e-16

module I

TREX1

0.93

0.85

2.25e-7

module II

VAT1

0.95

−1.13

1.68e-16

module II

SDC3

0.94

−2.27

1.16e-9

module II

FCGRT

0.94

−1.39

1.42e-10

module II

SLC46A1

0.94

−1.80

8.21e-18

module II

NAAA

0.94

−0.94

2.53e-20

module II

CSF1R

0.93

−1.54

1.43e-11

module II

MAN2B1

0.93

−0.44

5.77e-10

module II

ARRB1

0.92

−1.03

3.19e-9

module II

GAMT

0.92

−2.40

3.77e-19

module II

S100A4

0.92

−1.10

4.29e-12

  1. For every module the ten most correlated genes are listed with the following features: module membership, log2 fold change of the expression regulated by LPS, false discovery rate for the gene-wise differential expression (DE)