Fig. 1

DEIVA interface. a Data set selector, symbol locator, and highlight filters. b The density plot on a field of log2 FC vs log10 baseMean for a DGE statistical test result. Symbols selected in the symbol locator (shown in (a)) are shown as points with matching colors. In this example comparing samples highly enriched for RNA attached to ribosomes of Purkinje neurons (positive fold change) with samples of unspecific RNA in the same brain region (negative fold change). Locating a set of already known markers for Purkinje neurons immediately confirms that the markers are specifically enriched. Hexagonal bins are colored red based on the fraction of features within that region that pass the cut-off filters; currently set at a log10 FDR ≤ −1, at any fold-change. c Sortable table of expression values for the region selected in the density plot (shown in (b)). Twelve highly overrepresented genes are selected (grey rectangle) in the plot and their information is reflected in this table