| NS1-2 gene counts | NS1-2 dis gene counts | NS1-2 aadjusted p-values | NS1-2 disaadjusted p-values |
---|---|---|---|---|
Upregulated gene pathways | ||||
 Proteasome | 25 | 15 | 1.80E−15 | 2.30E−06 |
 Aminoacyl-tRNA biosynthesis | 14 | 9 | 4.80E−05 | 2.30E−02 |
 Focal adhesion | 27 | 22 | 6.90E−03 | 2.60E−02 |
 RIG-I-like receptor signaling | 14 | 10 | 5.60E−03 | 6.20E−02 |
 Toll-like receptor signaling | 16 | 13 | 2.10E−02 | 5.30E−02 |
 Pathways in cancer | 33 | 28 | 7.80E−02 | 4.80E−02 |
 NOD-like receptor signaling | 11 | 8 | 7.20E−02 | 1.90E−01 |
 Apoptosis | 12 | 11 | 1.90E−01 | 9.50E−02 |
 Regulation of actin cytoskeleton | 22 | 16 | 1.80E−01 | 3.80E−01 |
 Antigen processing and presentation | 11 | 9 | 3.00E−01 | 3.50E−01 |
 MAPK signaling | 24 | 22 | 3.00E−01 | 1.50E−01 |
 Gap junction | 10 | 10 | 3.60E−01 | 1.90E−01 |
 VEGF signaling | 9 | 9 | 3.80E−01 | 1.90E−01 |
 Cytokine-cytokine receptor interaction | - | 20 | - | 1.80E−01 |
Downregulated gene pathways | ||||
 Lysosome | 28 | 17 | 1.50E−11 | 4.30E−05 |
 Leukocyte transendothelial migration | 13 | 8 | 2.00E−01 | 6.30E−01 |
 Phosphatidylinositol signaling system | 9 | 9 | 3.30E−01 | 1.00E−01 |
 Toll-like receptor signaling | 10 | 7 | 3.70E−01 | 5.80E−01 |
 Regulation of actin cytoskeleton | 16 | 12 | 4.30E−01 | 7.30E−01 |
 Glycosaminoglycan degradation | 4 | 4 | 6.60E−01 | 7.50E−01 |
 Cell adhesion molecules | 11 | - | 7.10E−01 | - |
 p53 signaling | - | 6 | - | 8.50E−01 |
 Cytokine-cytokine receptor interaction | - | 13 | - | 6.80E−01 |
 Focal adhesion | - | 11 | - | 5.90E−01 |
 mTOR signaling | - | 5 | - | 5.40E−01 |