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Fig. 3 | BMC Genomics

Fig. 3

From: Detecting very low allele fraction variants using targeted DNA sequencing and a novel molecular barcode-aware variant caller

Fig. 3

Variant calling performance on 1% variants in panel N0030. X-axis is the number of false positives per megabase and y-axis is sensitivity. Solid lines, dashed lines, and dotted lines represent smCounter, MuTect, and VarDict respectively. Each point on the ROC curve represents a threshold value. a ROC curves of smCounter, MuTect, and VarDict base on 223 SNVs. b ROC curves of smCounter and VarDict on 49 indels. Note that MuTect does not call indels

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