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Table 3 DNA and RNA-metabolism related biological processes in response to neutron exposure

From: Comparison of gene expression response to neutron and x-ray irradiation using mouse blood

 

Term

N1d1_UP

N1d1_DN

N1d7_UP

N1d7_DN

GO:0006396

RNA processing

-

-

-

3.27E-18

GO:0050658

RNA transport

-

-

-

3.35E-06

GO:0000956

nuclear-transcribed mRNA catabolic process

-

-

-

0.0204

GO:0006260

DNA replication

-

9.59E-06

-

2.17E-06

GO:0006399

tRNA metabolic process

-

-

-

1.38E-06

GO:0006412

translation

-

0.0002

-

4.55E-11

GO:0008380

RNA splicing

-

0.0097

-

3.21E-13

GO:0034660

ncRNA metabolic process

-

-

-

2.23E-05

GO:0016071

mRNA metabolic process

-

0.0145

-

9.63E-14

GO:0006259

DNA metabolic process

-

2.06E-13

-

3.11E-11

GO:0006403

RNA localization

-

-

-

1.52E-06

GO:0045892

negative regulation of transcription, DNA-templated

-

0.0119

-

-

GO:0016444

somatic cell DNA recombination

-

0.0034

-

-

GO:0006401

RNA catabolic process

-

-

-

0.0427

GO:0016458

gene silencing

-

-

-

0.0358

GO:0006310

DNA recombination

-

0.0027

-

4.15E-05

GO:0051052

regulation of DNA metabolic process

-

-

-

0.0047

  1. Significantly enriched biological processes among genes downregulated in response to 1 Gy neutron irradiation at days 1 and 7. Benjamini-corrected p values are shown. Processes unique to neutrons are in bold. N1d1: 1 Gy neutron, day 1; N1d7: 1 Gy neutron, day 7. UP, upregulated; DN: downregulated