Fig. 9From: Single genome retrieval of context-dependent variability in mutation rates for human germlineAgreement between the 7-mer context-dependent Trek rate constants (in byr −1), determined in a single-genome manner, and the context-dependent substitution probabilities from the 1000 Genomes Project. a–c The correlation plots are shown for the substitution probabilities inferred [80] from three different (African, European and Asian) populations [81]. Only 7-mers with data present in both works were used for the comparisons. Overall, the plots highlight the good agreement between the two methods, and show the variation in substitution probabilities across different populations. This variation may be caused by genetic differences in those populations affecting genes/proteins involved in the background mutagenic and repair machineries, thus altering the spontaneous mutation ratesBack to article page