Table 2 Significantly upregulated contigs

  comp7819_c0_seq1

  Niemann-pick type c2

268.16

88.12

Cholesterol transport

  comp10576_c0_seq2

  UNC93a protein

74.60

43.64

Transmembrane transport

  comp13082_c0_seq1

  Membrane transport protein, putative

52.03

16.70

Transmembrane transport

  comp5926_c0_seq2

  Monocarboxylate transporter

28.09

14.45

Transmembrane transport

  comp9373_c0_seq2

  CD36 antigen

12.48

5.80

Cell adhesion/lipid binding

  comp6262_c1_seq3

  Gustatory receptor 64a

9.64

2.24

Chemosensory receptor

  comp9362_c0_seq1

  Ionotropic receptor 100a

9.14

2.02

Chemosensory receptor

  comp14845_c0_seq1

   OMPA-like protein

5.99

0.00

Wolbachia membrane

  comp13777_c0_seq18

   Permease

5.26

0.00

Transmembrane transport

  comp6505_c0_seq1

  Glucose transport protein

2.15

0.22

Glucose transport

  comp6457_c0_seq3

  Sulfakinin receptor

1.19

0.25

Chemosensory receptor

  comp13612_c0_seq1

  Chorion peroxidase

287.11

168.42

Oxidative stress

  comp8621_c0_seq1

  Anterior fat body protein

135.03

79.59

Redox process

  comp11151_c0_seq1

  Cytochrome p450

81.07

29.11

Oxidase

  comp8229_c0_seq2

  Cytochrome p450

50.12

26.71

Oxidase

  comp10103_c0_seq2

  Neuferricin homolog, cytochrome b5 domain-containing protein 2

25.33

12.90

Heme binding

  comp4282_c0_seq1

  Cytochrome p450

9.14

3.10

Oxidase

  comp6824_c0_seq1

  Short-chain dehydrogenase

6.79

1.43

Oxidoreductase

  comp10525_c0_seq3

  Brain chitinase and chia

196.30

85.85

Amino acid/carbohydrate metabolism

  comp7163_c0_seq1

  Chymotrypsin 1

179.35

69.13

Proteolysis

  comp11118_c0_seq1

  Gram negative bacteria binding protein 2

149.39

79.07

Carbohydrate metabolism

  comp8621_c0_seq1

  Anterior fat body protein

135.03

79.59

Lipoprotein

  comp9990_c0_seq1

  Phosphatidylcholine-sterol acyltransferase

87.08

32.92

Sterol/phospholipid metabolism

  comp2787_c0_seq1

  Serine protease

56.13

24.71

Proteolysis

  comp4890_c0_seq1

  Trypsin θ

47.87

12.96

Proteolysis

  comp12424_c0_seq4

  Pancreatic triacylglycerol lipase

45.47

19.55

Fat metabolism

  comp10453_c0_seq5

   Orf16-lacz fusion protein

42.79

0.88

Carbohydrate/glycoprotein metabolism

  comp12444_c0_seq3

  Glucosyl/glucuronosyl transferases

37.48

12.40

Carbohydrate/fatty acid metabolism

  comp10786_c0_seq2

  Serine protease

36.87

17.84

Proteolysis

  comp13425_c0_seq4

  Chitin metabolism protein

33.94

10.39

Peritrophic membrane metabolism

  comp11198_c1_seq2

  Serine 3-dehydrogenase

28.11

13.52

Amino acid metabolism

  comp8292_c0_seq2

  Galactose-specific C-type lectin

26.69

2.38

Carbohydrate metabolism

  comp9458_c0_seq1

  α chain crystal structure of β-glucosidase

18.76

5.39

Carbohydrate metabolism

  comp12611_c0_seq1

  β-hexosaminidase B

17.00

5.71

Carbohydrate/aminosugar metabolism

  comp9289_c0_seq1

  Serine threonine-protein kinase RIO1

16.31

3.07

Proteolysis

   comp13777_c0_seq6

   PG1 homology to homo sapiens

14.47

0.55

Organic compound metabolism

  comp12709_c0_seq1

  γ glutamyl transpeptidases

8.10

3.80

Amino acid metabolism

  comp5863_c0_seq3

  Acyltransferase

5.78

0.76

Protein modification

  comp12058_c1_seq1

  O-linked n-acetyl glucosamine transferase

5.75

0.27

Aminosugar metabolism

  comp6912_c0_seq1

  Glucosyl/glucuronosyl transferases

2.70

0.57

Carbohydrate/fatty acid metabolism

  comp9906_c0_seq2

  CDC42 protein

118.57

58.48

GTPase

  comp8210_c0_seq1

  Odorant-binding protein a10

49.07

17.86

Chemosensory protein serine/threonine kinase

  comp8312_c0_seq6

  GTP-binding protein di-ras2-like

24.21

13.00

GTPase

  comp10042_c0_seq3

  Stretchin- isoform v

5.39

0.27

Protein kinase

  comp309_c0_seq1

  ρ guanyl-nucleotide exchange factor

3.48

0.49

GTPase

  comp7767_c0_seq1

  Protein frg1 homolog

69.85

39.25

rRNA processing/Gene silencing/activation

  comp13326_c1_seq7

  Histone h2b

49.34

27.23

Gene silencing/activation

  comp10542_c0_seq1

Integrator complex subunit 12

27.74

10.71

snRNA processing

  comp6248_c0_seq1

Chromobox protein homolog 1

20.33

7.35

Gene silencing/activation

   comp13777_c0_seq25

   Ribosomal protein s10

13.45

3.44

Protein synthesis

  comp7336_c0_seq1

  Hect e3 ubiquitin ligase

11.86

5.97

DNA repair

  comp5798_c0_seq1

  Zinc finger protein 425

10.96

2.44

Transcription factor

  comp7025_c0_seq1

  Muts protein homolog 5-like

10.24

5.38

DNA repair

  comp8754_c0_seq1

  Mitochondrial 28 s ribosomal protein s29

8.11

0.00

Translation

  comp15539_c0_seq1

  TcasGA2_TC002223 Zinc finger domain containing protein

4.07

0.00

Transcription factor

  comp11749_c0_seq1

  Muts protein homolog 4

3.58

1.18

DNA repair

  comp2214_c0_seq1

  RNase H and integrase-like protein

3.60

0.74

DNA replication & repair

  comp13817_c0_seq21

  RNA/mRNA processing protein

2.14

0.14

RNA/mRNA processing

  comp13612_c0_seq1

  Chorion peroxidase

287.11

168.42

Ovarian follicle maturation

  comp5400_c0_seq1

  Synaptic vesicle protein

37.67

20.32

Neurotransmitter trafficker

  comp13425_c0_seq4

  Chitin metabolism protein

33.94

10.39

Morphogenesis

  comp11035_c0_seq1

  Voltage-dependent para-like sodium channel

27.45

7.89

Nerve impulse

  comp7184_c0_seq1

  Fasciculation and elongation protein ζ-2

22.96

6.83

Signal transduction/neural development

  comp14297_c0_seq1

  Major allergen bla g

22.81

5.58

Neurotransmitter binding

  comp11161_c0_seq1

  Neuroblast formation protein

15.44

3.44

Cell division/neuroblast formation

  comp11781_c0_seq19

  BMP-induced, dendrite morphogenesis factor

2.75

1.08

Neural development

  comp17984_c0_seq1

  Voltage-dependent pq type calcium channel

2.36

0.00

Neurotransmitter release

  comp11118_c0_seq1

  Gram negative bacteria binding protein 2

149.39

79.07

Pathogen binding

   comp10645_c1_seq8

   Cell wall-associated hydrolase

42.78

5.99

Bacterial cell wall degradation

  comp8292_c0_seq2

  Galactose-specific C-type lectin

26.69

2.38

Pathogen binding

  comp14485_c0_seq1

   Cell wall-associated hydrolase

12.27

1.61

Bacterial cell wall degradation

  comp4837_c0_seq1

  Salivary basic peptide-1

259.44

69.40

Salivary protein

  comp5901_c0_seq1

  Anti-platelet protein

66.88

39.76

Salivary protein

  comp6660_c0_seq1

  af378002_1 transposase

20.28

8.02

DNA integration

  comp13085_c0_seq2

  Reverse transcriptase

10.99

5.13

Reverse transcriptase

  comp12175_c0_seq4

  Retrovirus transposon polyprotein

7.68

3.39

Polyprotein

  comp13891_c0_seq14

  af378002_1 transposase

7.41

0.00

DNA integration

  comp14791_c0_seq1

  Uncharacterized protein K02A2

6.41

0.15

DNA integration

  comp14916_c0_seq1

  Retrovirus transposon polyprotein

4.76

0.00

Polyprotein

   comp13573_c0_seq26

   Endonuclease-reverse transcriptase

1.20

0.10

Reverse transcriptase