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Table 2 The 10 most differentially expressed genes in breast muscle tissue modern PeM broiler males compared to progenitor BPR broilers

From: RNA sequencing for global gene expression associated with muscle growth in a single male modern broiler line compared to a foundational Barred Plymouth Rock chicken line

FC

p-value

Symbol

Entrez gene name

Up-regulation

48.16

6.4E-05

PLIN1

perilipin 1

32.22

9.2E-07

LMOD2

leiomodin 2 (cardiac)

30.27

7.9E-04

CA3

carbonic anhydrase III

26.72

1.7E-07

MUSTN1

musculoskeletal, embryonic nuclear protein 1

20.96

1.2E-05

TNNT2

troponin T type 2 (cardiac)

19.97

4.8E-06

HSPB7

heat shock 27 kDa protein family, member 7 (cardiovascular)

18.12

1.0E-06

NOXO1

NADPH oxidase organizer 1

13.83

8.1E-05

PLN

phospholamban

12.99

2.8E-05

PCSK1

proprotein convertase subtilisin/kexin type 1

12.55

9.2E-04

MYBPC1

myosin binding protein C, slow type

Down-regulation

−13.36

9.6E-07

IL23R

interleukin 23 receptor

−11.39

4.2E-05

GPM6A

glycoprotein M6A

−8.81

1.5E-02

KL

klotho

−7.72

7.8E-05

AGMAT

agmatine ureohydrolase (agmatinase)

−7.72

1.1E-04

DKK2

dickkopf WNT signaling pathway inhibitor 2

−7.21

1.4E-03

GABRD

gamma-aminobutyric acid (GABA) A receptor, delta

−6.54

4.5E-03

FGB

fibrinogen beta chain

−6.49

1.1E-06

PPDPF

pancreatic progenitor cell differentiation and proliferation factor

−6.02

4.5E-06

ACE

angiotensin I converting enzyme

−5.93

3.6E-05

CD9

CD9 molecule