Comprehensive CircRNA expression profile and selection of key CircRNAs during priming phase of rat liver regeneration

Table 4 Key miRNAs during rat LR

miRNAs	Direct Target(s)	Variation tendency during rat LR	References	miRNAs	Direct Target(s)	Variation tendency during rat LR	References
miR-21	PELI1	up-regulated	[42]	miR-23b	SMAD3	down-regulated	[43]
	BTG2		[44]	miR-122	HO-1	up-regulated	[45–47]
	RHOB		[48]	miR-203	SOCS3	up-regulated	[49–53]
	PTEN		[54]	miR-382	PTEN	down-regulated	[35]
	FASLG		[55]		Akt	down-regulated	[35]
miR-221	P27	up-regulated	[56]	miR-16	-	down-regulated	[57]
	P57		[56]	miR-22	-	down-regulated	[57]
	ARNT		[58]	miR-23	-	down-regulated	[57]
miR-26a	CCND2	down-regulated	[59]	miR-24	-	down-regulated	[57]
	CCNE2		[59]	miR-29	-	down-regulated	[57]
miR-127	BCL6	down-regulated	[38, 60]	miR-30	-	down-regulated	[57]
	SETD8		[38, 60]	miR-31	-	down-regulated	[57]
miR-150	VEGF	down-regulated	[25]	miR-122a	-	down-regulated	[57]
miR-378	ODC1	down-regulated	[44]	miR-126	-	down-regulated	[57]
miR-181b	TIMP3	down-regulated	[61]	miR-145	-	down-regulated	[57]
miR-33	CDK6	down-regulated	[62]	miR-26b	-	up-regulated	[57]
	CCND1		[62]	miR-192	-	up-regulated	[57]
miR-34a	INHBB	up-regulated	[63]	miR-194	-	up-regulated	[57]
	MET		[63]

ISSN: 1471-2164