Fig. 4
From: Diet, gonadal sex, and sex chromosome complement influence white adipose tissue miRNA expression
Gonadectomy alters distribution of miRNAs in chow-fed mice. Distribution of female-to-male ratios (a) and XX-to-XY ratios (b) in highly expressed miRNAs. Ratios were calculated for each miRNA and log2-transformed in gonadally intact (Int) and gonadectomized (GDX) FCG mice fed a chow diet. Data for gonadally intact (Int) mice are identical to Fig. 3a–b, but binned in 0.1 increments and compared to data distribution for GDX mice. Each dot represents one of the 183 highly expressed miRNAs. Black bars represent median values. Distributions were significantly different for female-to-male ratios, but not for XX-to-XY ratios. p-values were calculated using the Wilcoxon rank sum test. F, female; M, male