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Fig. 5 | BMC Genomics

Fig. 5

From: Diet, gonadal sex, and sex chromosome complement influence white adipose tissue miRNA expression

Fig. 5

High fat diet alters miRNA expression levels in a sex-dependent and sex chromosome complement-dependent manner. Distribution of female-to-male ratios (a) and XX-to-XY ratios (b) in highly expressed miRNAs. Ratios were calculated for each miRNA and log2-transformed in gonadectomized (GDX) FCG mice fed a high fat diet (HFD). Data for chow-fed gonadectomized mice are identical to Fig. 4a–b. Distributions were significantly different for female-to-male ratios and for XX-to-XY ratios. p-values were calculated using the Wilcoxon rank sum test. F, female; M, male

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