Copy number loss
Higher levels of expression in ERalpha-negative tumors
Differentially expressed between breast cancer cells and mammary epithelial cells, highly expressed in MCF-7 cells
Expression was much higher in ERa-negative than in ERa-positive tumors.
miR-146: Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis
miR-146: rs2910164 were associated with increased risk of breast cancer in Chinese women
miR-146b-5p preferentially expressed in normal basal cells
Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers.
miR-149: rs2292832 were associated with increased risk of breast cancer in Chinese women
Down-regulated during lobular neoplasia progression compared to normal epithelium.
MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cells.
Differentially expressed between serum samples from patients with cancer and serum samples from healthy controls
Up-regulated greater than 2-fold in BC compared with NAT, potential target genes include members of RAS oncogenes.
Inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met
Inhibites breast cancer cell migration and invasion through targeting of oncoprotein c-Met.
Regulates beta-tubulin isotypes in MCF7 breast cancer cells.
Suppresses IGF2 and inhibits breast tumorigenesis by interfering with proliferation and survival signaling.
CTC (circulating tumour cells)-positive had significantly higher levels of miR-141 than CTC-negative MBC and controls.