From: A clustering-based approach for efficient identification of microRNA combinatorial biomarkers
MiRNA name | PMID | Description |
---|---|---|
hsa-mir-18a | 16754881 | Copy number loss |
 | 19684618 | Higher levels of expression in ERalpha-negative tumors |
 | 19624877 | Differentially expressed between breast cancer cells and mammary epithelial cells, highly expressed in MCF-7 cells |
 | 21755340 | Expression was much higher in ERa-negative than in ERa-positive tumors. |
hsa-mir-146b | 16461460 | Overexpressed |
 | 19190326 | miR-146: Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis |
 | 18634034 | miR-146: rs2910164 were associated with increased risk of breast cancer in Chinese women |
 | 21409395 | miR-146b-5p preferentially expressed in normal basal cells |
 | 21472990 | Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. |
hsa-mir-149 | 18634034 | miR-149: rs2292832 were associated with increased risk of breast cancer in Chinese women |
hsa-mir-224 | 21953071 | Down-regulated during lobular neoplasia progression compared to normal epithelium. |
 | 22809510 | MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cells. |
hsa-mir-452 | 22353773 | Differentially expressed between serum samples from patients with cancer and serum samples from healthy controls |
hsa-miR-365 | 18812439 | Up-regulated greater than 2-fold in BC compared with NAT, potential target genes include members of RAS oncogenes. |
hsa-mir-340 | 21225860 | Inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met |
 | 21692045 | Inhibites breast cancer cell migration and invasion through targeting of oncoprotein c-Met. |
hsa-mir-100 | 21634028 | Regulates beta-tubulin isotypes in MCF7 breast cancer cells. |
 | 22926517 | Suppresses IGF2 and inhibits breast tumorigenesis by interfering with proliferation and survival signaling. |
hsa-mir-141 | 18376396 | Downregulated |
 | 22952344 | CTC (circulating tumour cells)-positive had significantly higher levels of miR-141 than CTC-negative MBC and controls. |