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Table 2 Gene set enrichment of miR2916 target genes

From: Plant miRNAs found in human circulating system provide evidences of cross kingdom RNAi

Category

Term

P Value

Genes

KEGG_PATHWAY

ptr05202: Transcriptional misregulation in cancer

0.011556

MEN1, LDB1, TLX1

GOTERM_BP_DIRECT

GO:0043484 ~ regulation of RNA splicing

0.02339

SON

INTERPRO

IPR000467:G-patch domain

0.025805

SON

UP_KEYWORDS

DNA-binding

0.028196

TBX2, PPP1R10, H2AFX, TLX1

INTERPRO

IPR014720: Double-stranded RNA-binding-like domain

0.029124

SON

GOTERM_CC_DIRECT

GO:0071011 ~ precatalytic spliceosome

0.033471

SON

SMART

SM00443:G_patch

0.036062

SON

GOTERM_BP_DIRECT

GO:0000910 ~ cytokinesis

0.036161

SON

GOTERM_MF_DIRECT

GO:0003723 ~ RNA binding

0.037823

SON, TDRKH

GOTERM_CC_DIRECT

GO:0000781 ~ chromosome, telomeric region

0.046328

PPP1R10, H2AFX

GOTERM_BP_DIRECT

GO:0006397 ~ mRNA processing

0.053776

SON

GOTERM_BP_DIRECT

GO:0000226 ~ microtubule cytoskeleton organization

0.058753

SON

GOTERM_BP_DIRECT

GO:0032092 ~ positive regulation of protein binding

0.063706

MEN1, PLXND1

GOTERM_CC_DIRECT

GO:0000785 ~ chromatin

0.073822

MEN1, PPP1R10

UP_KEYWORDS

Nucleus

0.081889

TBX2, PPP1R10, H2AFX, TLX1

GOTERM_CC_DIRECT

GO:0005634 ~ nucleus

0.08342

MEN1, TBX2, LDB1, MKNK2, H2AFX, MID1IP1, TLX1

GOTERM_BP_DIRECT

GO:0051726 ~ regulation of cell cycle

0.091709

SON

  1. This table summarized the gene set enrichment of miR2916 targets. The human genes listed here were predicted to be targeted by plant miR2916 through sequence analysis. The terms were originated from the web based tool DAVID [33]