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Table 1 (a) Top upregulated and (b) top down-regulated DEGs in vitiligo (VL)-blood expression profile

From: Vitiligo blood transcriptomics provides new insights into disease mechanisms and identifies potential novel therapeutic targets

Entrez ID Gene Symbol Gene Title p-value Fold-Change
a
2201 FBN2 fibrillin 2 0.0345 1.5
1577 CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0315 1.5
23253 ANKRD12 ankyrin repeat domain 12 0.0236 1.4
1545 CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0069 1.4
b
9636 ISG15 ISG15 ubiquitin-like modifier 0.0172 −4.2
3434 IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0168 −4.0
710 SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.008 −4.0
10964 IFI44L interferon-induced protein 44-like 0.0283 −3.6
4599 MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 0.0098 −3.5
3437 IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0133 −3.5
4277 MICB MHC class I polypeptide-related sequence B 0.0085 −3.3
653361///654816///654817 NCF1///NCF1B///NCF1C neutrophil cytosolic factor 1///neutrophil cytosolic factor 1B pseudogene///neutrophil 0.0436 −2.7
8638 OASL 2′-5′-oligoadenylate synthetase-like 0.0334 −2.7
10581 IFITM2 interferon induced transmembrane protein 2 0.0342 −2.7
  1. Fold Change; a “positive” fold change indicates an upregulation and a “negative” fold change indicates a down-regulation in peripheral blood of VL patients vs. healthy controls