Table 4 Significantly enriched functions in the set of genes differentially expressed in colonocytes isolated from rats fed a high-protein diet compared to rats fed a normal-protein diet. ‘Genes’ indicates the number of genes differently expressed implicated in the function, ‘Up’ and ‘Down’ indicate the number of genes upregulated and downregulated, respectively
From: Epithelial response to a high-protein diet in rat colon
Function annotation | p-value | Genes | Up | Down |
|---|---|---|---|---|
Cell death | 4.89E-02 | 103 | 18 | 85 |
Autophagy | 2.96E-03 | 10 | 1 | 9 |
Neoplasia of epithelial tissue | 1.83E-02 | 8 | 3 | 5 |
Senescence of cells | 2.27E-02 | 3 | 0 | 3 |
Organization of mitochondria | 2.27E-02 | 3 | 0 | 3 |
Anoïkis of carcinoma cell lines | 9.13E-03 | 2 | 0 | 2 |
Morphology of intestinal cell lines | 9.13E-03 | 2 | 0 | 2 |
Polarity of cells | 4.81E-02 | 2 | 0 | 2 |