Fig. 4From: De novo mutational profile in RB1 clarified using a mutation rate modeling algorithmExon specific and localized enrichment of missense mutations in RB1. a Comparison of the overall observed number of mutations to the simulated frequency of missense mutations in both RB and ExAC datasets. b Comparison of the observed number of mutations to the simulated frequency of missense mutations in RB, across exons 2 to 27Back to article page