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Table 1 Gene Ontology (GO) analysis of positively selected genes in Chow Chow

From: The origin of chow chows in the light of the East Asian breeds

GO terms

P Value

Enrichment fold

Genes mentioned in the main text

Proline biosynthetic process

0.002

42.946

-

Proline metabolic process

0.004

30.062

-

Adult behavior

0.01

5.826

ASIP, TSHR, ABAT

Glutamine family amino acid biosynthetic process

0.015

15.822

-

Oxidation reduction

0.025

2.039

-

Lysosomal transport

0.025

12.025

-

Intracellular transport

0.03

1.983

-

Feeding behavior

0.031

5.809

ASIP

Muscle cell differentiation

0.032

4.141

SMARCD3, TSC1, MKL2

Heart morphogenesis

0.036

5.491

SMARCD3, COL5A1, MKL2

Positive regulation of striated muscle development

0.039

50.104

ADRB2, MKL2

Positive regulation of muscle development

0.039

50.104

ADRB2, MKL2

Vacuolar transport

0.04

9.394

-

Lipid biosynthetic process

0.042

2.482

-

Respiratory gaseous exchange

0.049

8.351

FUT8

PcG protein complex

0.005

28.404

-

Pyrroline-5-carboxylate reductase activity

0.001

55.247

-

Oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor

0.016

15.346

-

Oxidoreductase activity, acting on the CH-NH group of donors

0.039

9.525

-

Steroid dehydrogenase activity

0.044

8.911

-

Hsa00150:Androgen and estrogen metabolism

0.005

10.779

-