Table 1 Proteins information from iTRAQ data and MRM validation in comparison groups of 1-IB-vs-1-Rib and 1-IB-vs-2-IB
Comparison | Protein | NCBI description | Mean ratio of iTRAQ | Mean ratio of MRM | P-value of MRM |
|---|---|---|---|---|---|
1-IB-vs-1-Rib | CL1241.Contig2_All | transforming growth factor, beta-induced | 1.44 | 1.56 | 0.09 |
CL2864.Contig2_All | laminin, α-4 | 1.68 | 2.03 | 0.00 | |
CL2923.Contig2_All | osteoglycin precursor | 1.02 | 1.88 | 0.02 | |
CL664.Contig4_All | fibronectin precursor | 0.42 | 0.15 | 0.00 | |
Unigene109_All | collagen α2(XI) | 0.20 | 0.06 | 0.02 | |
Unigene13384_All | Tnc protein | 1.91 | 2.31 | 0.01 | |
Unigene16932_All | collagen α3(VI) chain | 0.77 | 0.89 | 0.19 | |
Unigene19583_All | collagen α1(VI) chain | 0.81 | 0.50 | 0.00 | |
Unigene441_All | osteomodulin | 1.59 | 3.90 | 0.00 | |
Unigene7040_All | ictacalcin | 0.11 | 0.08 | 0.00 | |
Unigene8331_All | decorin variant 1 | 1.14 | 1.73 | 0.00 | |
1-IB-vs-2-IB | CL1241.Contig2_All | transforming growth factor, beta-induced | 1.52 | 1.50 | 0.12 |
CL2923.Contig2_All | osteoglycin precursor | 1.37 | 1.58 | 0.06 | |
CL360.Contig2_All | myosin heavy chain fast skeletal type 1 | 0.63 | 0.61 | 0.09 | |
Unigene109_All | collagen type α2(XI) | 1.09 | 1.43 | 0.74 | |
Unigene12601_All | myosin heavy chain fast skeletal type 3 | 2.40 | 6.56 | 0.05 | |
Unigene13384_All | Tnc protein | 2.54 | 2.03 | 0.01 | |
Unigene16459_All | heat shock protein | 1.11 | 1.32 | 0.17 | |
Unigene18499_All | collagen α6(VI) chain | 1.08 | 1.17 | 0.59 | |
Unigene30256_All | collagen α1(XII) chain-like | 1.38 | 1.23 | 0.34 | |
Unigene3121_All | calsequestrin 1a precursor | 0.70 | 0.26 | 0.05 | |
Unigene441_All | osteomodulin | 1.31 | 1.98 | 0.02 | |
Unigene7040_All | ictacalcin | 1.19 | 1.17 | 0.82 | |
Unigene8331_All | decorin variant 1 | 1.23 | 1.41 | 0.00 |