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Fig. 3 | BMC Genomics

Fig. 3

From: An approach of identifying differential nucleosome regions in multiple samples

Fig. 3

Validation for Dimnp using the manually identified DNRs as a standard. Shown are receiver operating characteristic (ROC) curves in comparing the DNRs by Dimnp and the manually identified DNRs. The manual DNRs between two cell types, termed as “the manual”, are the regions where the ratio of the normalized reads count between the two cell types is either ≥1/0.6 or ≤ 0.6. The manual DNRs of three cell types (“the manual-3”) are formed by polling the manual two cell types DNRs together. The pooled manual DNRs are used as a standard to test the performance of both Dimnp and literature tool Danpos [7]. The area under the curve (AUC) is 0.87 for Dimnp

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