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Fig. 1 | BMC Genomics

Fig. 1

From: A meta-analysis reveals complex regulatory properties at Taf14-repressed genes

Fig. 1

Taf14 negatively regulated genes show distinct regulatory features. These genes are mostly stress-related, their promoters mainly contain a TATA box and SAGA complex is mostly responsible for loading TBP to these promoters. Transcription of these genes is also highly regulated by a distinct set of regulators. Besides positive regulation by the stress related activator Msn2/4, transcription regulation of Taf14 repressed promoters is dominated by negative regulators of transcription. These include the negative co-regulators histone de-acetylases (Hda1 and Rpd3), TBP repressors Mot1 and NC2 (Ncb2-Bur6), Cyc8-Tup1 repressor complex, and two members of Mediator complex, Srb10 and the Mediator tail module. Repressing elements of transcription are illustrated in red and activating elements are in green

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