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Fig. 5 | BMC Genomics

Fig. 5

From: A vast genomic deletion in the C56BL/6 genome affects different genes within the Ifi200 cluster on chromosome 1 and mediates obesity and insulin resistance

Fig. 5

Impaired insulin sensitivity in animals carrying the NZO Ifi200 gene cluster. a Blood glucose levels in Nob3.14 B/B and Nob3.14 N/N female mice under HFD conditions. b Female congenic mice (Nob3.14 B/B (n = 8) and Nob3.14 N/N(n = 10)) were fasted overnight and received an oral bolus of 2 g/kg body weight of glucose and blood glucose (b) and insulin levels (c) were measured at the indicated time points. d Calculation of the HOMA-IR of congenic mice (Nob3.14 B/B, n = 6; Nob3.14 N/N, n = 9). Data are presented as mean ± SEM. **p < 0.01, ***p < 0.001 by t-test

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BMC Genomics

ISSN: 1471-2164

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