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Fig. 1 | BMC Genomics

Fig. 1

From: Genome-wide identification of direct HBx genomic targets

Fig. 1

Functional analysis of protein-coding genes potentially regulated by HBx. a Biological Pathways (KEGG, REACTOME), Biological Processes (GO) and Protein families, domains and important sites (InterPro) over-represented (Benjamini-corrected p-value < 5Ă—10−2) from the analysis of ~5500 protein-coding genes with HBx-binding sites are shown. In each plot, the categories are in descending order with respect to the associated gene number, with the corresponding color scale of p-values shown on the right. b Validation of HBx occupancy on selected gene promoters in independent ChIP experiments. ChIP results are expressed as Fold Induction (FI) of the % of Input. Histograms show the mean from three independent experiments; bars indicate SD. P-values: * 0,02 ≤ P < 0,05; ** 0,01 ≤ P < 0.02; *** 0,005 ≤ P < 0.01. Gene specific promoter primer pairs are detailed in Additional file 1: Table S6

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