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Fig. 5 | BMC Genomics

Fig. 5

From: Exploratory bioinformatics investigation reveals importance of “junk” DNA in early embryo development

Fig. 5

Presence of some repeats strongly correlated with activation of gene expression during 2C stage in a dosage- and distance -dependent manner. The heights of the bars indicate average fold-change in late 2-cell stage compared to early 2-cell. Significant deviations from zero are indicated by stars. The numbers on the bar represent the number of genes affected. The MT2 repeats in (a) and (b) can be MT2B, MT2B1, MT2B2, MT2_Mm, or MT2C_Mm. In (c) and (d), Alu family repeats mostly represent B1 elements. e Result from multiple linear regressions shows that SINE and LTR elements are correlated with gene expression change. f Correlation of the number of Alu family repeats in promoters and broad gene expression in various cells and tissues. Error bar shows standard error calculated from replicates. R1 and J1 are mouse embryonic stem cell lines

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