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Fig. 3 | BMC Genomics

Fig. 3

From: Understanding the response to endurance exercise using a systems biology approach: combining blood metabolomics, transcriptomics and miRNomics in horses

Fig. 3

Activators and repressors of the regulatory network. a The regulatory network was driven by different transcription factors able to up- or down regulate the glucose and lactate concentration (EP300, CREBBP, SIRT1, BCL6, and REBL2). b The EP300 and SIRT1 transcription factors could be regulated by the expression of let-7b-5p and miR-223-3p, respectively, and RBL2 might be inhibited by miR-192-5p. In the figure, the node color intensity indicates the associated expression level: red = over-expression at T1 and green = under-expression at T1

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BMC Genomics

ISSN: 1471-2164

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